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via <br /> CHEVRON Regular Gasoline Page 9 of 10 <br /> protein-isoparaffin complex accumulates in the kidney tubules causing <br /> significant, cell death and regrowth. It is thought that this continuous <br /> kidney injury may contribute to the eventual development of the tumors. <br /> Tht, data above is obtained from studies sponsored by the American <br /> Petroleum Institute (API). <br /> 32. ADDIT10KAL HEALTH DATA <br /> ADDITIONAL HEALTH DATA COMMNT: <br /> This product contains benzene. The OSHA Benzene Standard (21i CFR <br /> 1910.1028) contains detailed requirements for training, expoNure <br /> monitoring, respiratory protection and medical surveillance triggered by <br /> the exposure level. Refer to the OSHA Standard before using this product. <br /> Repeated or prolonged breathing of benzene vapors has been ausociated with <br /> the development of chromosomal damage in experimental animal:; and various <br /> blood diseases in humans ranging from aplastic anemia to leuKemia (a form <br /> of cancer) . All of these diseases can be fatal. No birth defects have <br /> been shown to occur in pregnant laboratory animals exposed to doses not <br /> toric to the mother. However, some evidence of fetal toxicity such as <br /> delayed physical development has been seen at such levels. The available <br /> information on the effects of benzene on human pregnancies i:s inadequate <br /> but it has been established that benzene can cross the human placenta. <br /> This product contains n-hexane. Prolonged or repeated skin t:ontact or <br /> breathing of vapors may cause nerve damage characterized by progressive <br /> weakness and numbness in the arms and legs. Recovery ranges from no <br /> recovery to complete recovery depending upon the severity of the nerve <br /> damage. <br /> This product contains toluene. Toluene has been reported to decrease <br /> immunological responses in test animals. It has also Been reported that <br /> when young rats •#ere exposed to 1000 ppm toluene for 14 hour:. daily, for <br /> two weers, irreversible hearing loss was detected. The same daily exposure <br /> to 700 ppm for as long as 16 weeks was without effect. Since the lever <br /> necessary to produce hearing loss is greater than 7 times the 1987-85 <br /> ACGIH TLV for toluene, worker exposures at or below 100 ppm is not <br /> expected to cause any adverse effect. There are also report= that chronic <br /> abusers (glue sniffers, solvent huffers3 if solvents containing toluel,e <br /> have suffered liver, kidney and brain damage. Scientific studies on <br /> toluene have failed to demonstrate birth defects in rats and mice. <br /> However, toluene has been shown to cause delayed growth and extra ribs in <br /> the offspring of rats and mice at inhaled doses (266-399 ppm) that were <br /> non-toxic to the mother. Toluene has not conclusively been shown to cause <br /> adverse reproductive effects in humans. <br /> This product contains xylene, a chemical that has been reported to cause <br /> developmental toxicity in rats and mice exposed by inhalation during <br /> pregnancy. The effects noted consisted of delayed development and minor <br /> skeletal variations; additionally, when pregnant mice were exposed by <br /> ingestion to a level that killed nearly one-third of the test group, <br /> lethality (resorptions) and malformations (primarily cleft palate) <br /> Revision dumber: 13 Revision Date: 03/24190 KSDS Number: 000363 <br /> MDA - No Data Available NA - Not Applicable <br />