Laserfiche WebLink
UNLEADED GASOLINE(UNBRANDED) MSDS No.APPC975 Ver. 1 <br /> Chronic toxicity studies have been completed for MTBE. In these studies, B6C3F1 mice and <br /> F344 rats were exposed to 400, 3000, or 8000 ppm MTBE vapors, 6 hrs/day, 5 days/week <br /> for life. Few adverse effects were noted for either rats or mice. <br /> Male and female mice exposed to 8000 ppm MTBE vapors developed a slightly higher <br /> incidence of benign liver tumors during their lifetime. No other adverse effects or increases <br /> in tumor incidences were found. <br /> Male and female rats exposed to high concentrations of MTBE vapors developed an <br /> increasing incidence of chronic progressive kidney damage, an effect typically noted in aging <br /> rats. These effects were most severe in 3000 and 8000 ppm exposure groups and were <br /> accompanied by an increased incidence of kidney tumors (males only). These findings are <br /> consistent with kidney damage associated with accumulation of protein in cells, an effect <br /> which may be unique to the male rat. Benign testicular tumors were numerically increased in <br /> high dose MTBE male rats, but this is an age-related lesion which typically occurs in a very <br /> high proportion of control untreated rats. <br /> MTBE does not appear to be a mutagen. <br /> All of these effects either occur in tissues prone to the development of tumors or may occur <br /> by a mechanism not considered relevant to humans. The significance of these findings for <br /> human health hazards estimation is unclear. Furthermore, IARC has determined that MTBE <br /> is not classifiable as to its carcinogenicity to humans (Group 3). <br /> 12. ECOLOGICAL INFORMATION <br /> Not Available <br /> 13. DISPOSAL CONSIDERATIONS <br /> Waste Disposal Consult an environmental professional to determine if state or federal regulations would <br /> Methods classify this material as a hazardous waste. Use only approved transporters, recyclers, <br /> treatment, storage or disposal facilities. Comply with all federal, state and local laws <br /> pertaining to waste management. <br /> 14. TRANSPORT INFORMATION <br /> UN Proper Shipping Name Gasoline <br /> UN Hazard Class 3 <br /> UN Number UN1203 <br /> UN Packing Group PGII <br /> Print Date:05/19/2003 Page 7 of 8 <br />