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ISSUED: BK08-T 18 1004 CARDINAL SAFETY DATA SHEET REFERENCE: KO8-T002 Additional information Repeated dose toxicity - male and female rat- lowest observed adverse effect level - 2500 m k Additional information To the best of our knowledge, the chemical, physical, and toxicological ro erties have not been thoroughly investigated Amorphous Silica 112926-00-8 Acute toxicity no data available Acute toxicity: Inhalation no data available Acute toxicity: Dermal no data available Skin irritation no data available Eye irritation no data available Respiratory or skin sensation no data available Germ cell mutagenicity no data available Carcinogenicity: IARC: Group 3: not classifiable as to its carcinogenicity to humans ACGIH no component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH NTP no component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP OSHA no component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA Reproductive toxicity no data available Specific target organ toxicity - single no data available exposure Specific target organ toxicity - repeated no data available exposure Aspiration hazard no data available Additional information Amorphous silica is not classified as to its carcinogenicity to humans, however, crystalline silica inhaled in the form of quartz or cristobalite from occupational sources is carcinogenic to humans (Group 1, IARC). Therefore, amorphous silica should be handled as if possessing the same hazards as the crystalline form. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Additional information Stomach - irregularities - based on human evidence Barium Sulfate 7727-43-7 Acute toxicity - inhalation No data available Acute toxicity - Dermal No data available Skin irritation No data available Eye irritation No data available Respiratory or skin sensation No data available Germ cell mutagenicity - mouse - No reported data micronucleus test Carcinogenicity - rat- intrapleural - Equivocal tumorigenic agent by RTECS criteria. Lungs,Thorax, or tumorigenic Respiration: Tumors IARC No component of this product present at levels greater than or equal to 0.1% is identified as a probable, possible, or confirmed human carcinogen b IARC ACGIH No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH NTP No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP OSHA No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA Reproductive toxicity No data available Specific target organ toxicity - single No data available exposure Specific target organ toxicity - repeated No data available exposure Aspiration hazard No data available Additional information Prolonged inhalation of dust may cause baritosis, a benign pneumoconiosis. If ingested, the presence of soluble barium salts as impurities may cause toxic reactions due to bioaccumulation., Damage to the lungs., To the best of our knowledge, the chemical, physical, and toxicolo ical properties have not been thoroughly investigated. Additional information Stomach irregularities - based on human evidence Carbon'Black 1333-86-4 LD50 Oral - Rat > 8,000 mg/kg, male and female OECD Test Guideline 401 LD50 Inhalation - Rat No data available Page 5 of 14