COMPLIANCE INFO_2019 - Laserfiche WebLink

Home Browse Search

ISSUED: 8/22/2018 ,,,4CARDINAL SAFETY DATA SHEET REFERENCE: BK08-TO02 LD50 Dermal - Rabbit > 3,000 mg/kg Skin corrosion irritation No skin irritation - 24 h OECD Test Guideline 404 Eye dam a e/irritation - Rabbit No eve irritation OECD Test Guideline 405 Respiratory/skin sensitization - Guinea pig Did not cause sensitization on laboratory animals, (OECD Test Guideline 406 Germ cell mutagenicity Ames test S. typhimurium, negative Hamster- Ovary Negative DNA repair- Rat- Female Negative Carcinogenicity - Rat-Inhalation Tumorigenic: Carcinogenic by RTECS criteria. Lungs, Thorax, or Respiration: Tumors. This product is or contains a component that has been reported to be possibly carcinogenic based on its IARC, ACGIH, NTP, or EPA classification. Limited evidence of carcinogenicity in animal studies. IARC 2B - Group 213: Possibly carcinogenic to humans carbon black NTP No component of this product present at levels greater than or equal to0.1% is identified as a known or anticipated carcinogen by NTP OSHA No component of this product present at levels greater than 0.1% is identified as a carcinogen or potential carcinogen by OSHA Reproductive toxicity No data available Organ toxicity Specific target organ toxicity - single exposure: No data available Organ toxicity Specific target organ toxicity - repeated exposure: No data available Aspiration hazard No data available Additional Information RTECS: FF5800000 To the best of our knowledge, the chemical , physical, and toxicological properties have not been throughly investigated. Crystalline Silica 14808-60-7 Acute Inhalation toxicity no data available Acute Dermal toxicity no data available Skin irritation no data available eve irritation no data available Respiratory or skin sensation no data available Germ cell mutagenicity no data available Carcinogenicity Limited evidence of carcinogenicity in human studies IARC Group 1: Carcinogenic to humans (Quartz) ACGIH No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH NTP Known to be human carcinogen (Quartz) OSHA No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA Reproductive toxicity no data available Specific target organ toxicity - single no data available exposure Specific target organ toxicity - repeated may cause damage to organs through prolonged or repeated exposure exposure - inhalation Aspiration hazard no data available Additional information Prolonged inhalation of crystalline silica may result in silicosis, a disabling pulmonary fibrosis characterized by fibrotic changes and miliary nodules in the lungs, a dry cough, shortness of breath, emphysema, decreased chest expansion, and increased susceptibility to tuberculosis. In advanced stage, loss of appetite, pleuric pain, and total incapacity to work. Advanced silicosis may result in death due to cardiac failure or destruction of lung tissue. Crystalline silica is classified as group 1 "known to be carcinogenic to humans" by IARC and "sufficient evidence" of carcinogenicity by the NTP.,The chronic health risks are associated with respirable particles of 3-4 um over protracted periods of time. Currently, there is a limited understanding of the mechanisms of quartz toxicity, including its mechanisms for lung carcinogenicity. Additional studies are needed to determine whether the cell transforming activity of quartz is related to its carcinogenic potential. Additional information Liver- Irregularities - based on human evidence Limestone 1317-65-3 Draize test rabbit eye 750 u 24H severe Draize test rabbit skin 500 m /24H moderate Oral rat: LD50 6450 mg/kg ACGIH IARC NTP CA Prop 65 Not listed Epidemiology No information available I Teratogenicity No information available Reproductive effects No information available Mutagenicity No information available 1 Page 6 of 14 i