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tylbutylami-no)-3-methylquinoline d' 1-Chloro-2-methylpropene
<br /> NO 6CaOCtyH O -. 2CHCIp+(CH,COO),Ca + 2Ca(OH) + amole as a saponin which kills or stuns fis
<br /> CaCI,+6{8,0. May also be pr
<br /> by carefully controjled ing them inedible. Structure: Marker. Rc
<br /> ei minabon of methane: Faith, Keyes A Clark's Industrial 947. 3479(1939); Marker et al. ibid.62,2
<br /> emiaa/s, F. A. Lowmheim, M. K. Moran, Bda, (Wiley- On hydrogenation the 3p,60-isomer (0-ch.
<br /> terscimee,New York,4th ed.. 1975)pp 266-269. Review duced.
<br /> N<r of toxicology: L. R. Pohl. Rev. Biochem. Toxirol. 1,79-108
<br /> (1979). Review of Carcinogenicity studies: IARC Mono.
<br /> Yellow crystals from benzene + petr ether or from acetic ::graph,20,401.427(1979).
<br /> acid. Skin irritant, mp 86-87. d]aa 1.6867. by 315'. Prac. 'S Highly refractive, nonflammable, heavy. very volatile, Pea :o-,
<br /> tically insol in water. Sol in ale. Moderately sol in ether, 'tweet-tasting liquid: characteristic odor. 411 1.484. by
<br /> benzene 64621 Solidif-63.5. al 1.4476. Forms a constant boil-
<br /> Cautian: See 1-Chloro-2.4-dinitrobenzene, ( leg mixture with 7%ale.boiling at 59-. d 1.474 to 1.478 for ��I, D
<br /> U.S.P.chloroform conlg 0.5-1%ethanol as stabilizer. One u
<br /> 2107. 0-Chloroethyl Acetate. 2-Chlomelhano( insert. •'ml dissolvea in about 200 ml water at 25'. Misc with alto- Cx
<br /> C, is
<br /> HtC10,;mol wt 122.55. C 39.20%, H 5.76%, Cl 28.94%, " bol,benzene,ether, petr ether.carbon tetrachloride carbon s
<br /> O 26.11%. CH,COOCH,CH,CI. Preps from ethylene oxide disulfide oils. Pure chloroform is light sensitive and reagent y
<br /> and acetyl chloride: Gustus,Stevens, J. Am. Chem. Sac.55, grade chloroform usually contains 0.75%ethanol as stabiliz-
<br /> 378 (1933). er. Protect from light and keep Cool. LDsa orally in rats: w
<br /> s
<br /> Liquid, by 145. die 1.1460. ng 1.4234. Flash pt 53.89° 2.18 g/kg,H.F.Smyth er al..Am. Ind. Hyg. Assoc.J.23,95 it
<br /> (closed cup): Ind. Eng. Chem.32, 890(1940). Practically (1962). bx
<br /> insol in water; sol in alcohol. Human Taxiciey: Inhalation of large doses may Cause
<br /> USE: Gasoline additive. Henderson, U.S. pat. 3,179,506 hypotension. respiratory and myocardial depression and Needles from methanol, mp 273-276'. [
<br /> (1965 to Shell). i death. Banned by FDA from use in drug,cosmetic and food roform or isopropanol). Less sol in meth
<br /> packaging products in 1976. This substance has been listed isopropanol then tigogenin.
<br /> 2108. N-(2-ChloroethyUdibenzylamine Hydrochloride. I „a Carcinogen by the EPA: Second Annual Repos on Car. Diacetate,crystals from dil methanol,m
<br /> N-(2-Chloroshyq•N-(phenylmethyl)benzenemethanami^e .-,,4_ xinogens(NTP 81-43.Dec. 1981)pp 78-80. Dibenzoate. crystals from methanol +
<br /> hydrochloride; f1-chloroethyldibenzylamine hydrochloride; '. USE: As a solvent for fats.oils. rubber. alkaloids. waxes, 200,5-204.5'. [.% +9.3'(chloroform).
<br /> N,N-dibenzyl•p-chloroethylamine hydrochloride; N.N-di- '',gutta-pncha,resins;as cleansing agent:in fire extinguishers
<br /> benzylaminoethyl chloride hydrochloride; Dibenamine by. I _.. -,to lower the freezing temp of Carbon tetrachloride; in the 2114. 1-Chlorohexane. n-Hexyl chlorii
<br /> drochlonde. Ct H„CIN.HCI;mol wt 296.23. C 64.87%,H `:libber industry. wt 120.62. C 59.74%, H 10.86%, Cl 29.4
<br /> 6.46% Cl 23.94, N 4.73%. (C,H,CH )pNCH CH,CI.HCI. rxeaAr CAT: Pharmaceutic aid (solvent). CH Cl. Prepd from I•hexenoi by treats
<br /> Preps: Minn.). A.47. 206(pat. 82,208(1 31 to Both- MEW CCT(vnn: Has been used m an anesthetic,and as a HCI: Henry, Chem. Zenir. 1905,11,214:
<br /> ringer. ann.). CA.47, 2206(1953). MEW
<br /> and antispasmodic. or with PCI, + ZnCI¢: Clark, Straight.
<br /> Crystals,mp 192',also given m 180-181-(the free base is Can.13]23, III,77(1929).
<br /> an oily liquid). Practically insol in water near neutrality,but 'n',2112. Chlorogenic Acid. 3-((3-(3,4-11(hydroxyphenyD-I- Mobile liquid. die 0.8780. bp,. 134'. i
<br /> Sol in dil acids(21/6 at pH 2.1. 1%at pH 2.4 and 0.5%al pH "axa2.pmpenyljoxy]-l•4,5-irihydroxycyclohexanmarboxylic Streighl, loc. cit.); ng 1.4195(Mumford,
<br /> 2.7),in 95%alcohol and in propylene glycol. Stable in acid 'acid; 1,3,4,5-tsrohydroxycyclohexanacarboxylic acid 3-(3,4- Svc, 1950, 75). lnsol in water. Refluxi
<br /> win, but rapidly loans activity in neutral or alkaline wins. 'dihydroxycinnamote); 3Kaffcoylquinic add: 343.4-dihydr- NaOH decomposes 1-chlorohemia:to 1-h
<br /> LDw S.C. in mice: 800 mg/kg. Nickerson. Nomaguchi. ✓. oxydnmmoyNufnic add. CUHuO,: mol wt 354.30. C
<br /> Pharmacal. Exp. Thee 101,379(1951). 54.24%H 5.12%•O 40.649r. Important factor in plant me. 2115. a-Chlorohydrin. 3•Chloro-1,2
<br /> MER" CAT: Adrenergic blocker: diagnostic aid (pheo- tabolism. Isoln from green Coffee beans: Freudenberg. Ber. chloro-1.2-dihydroxypropane: a-monoch
<br /> chromocytoma). I 33;237(1920). Chlorogenic add and its isomers isachioro• dihydroxyiwpropyl chloride: glycerol *-in
<br /> c add and neoctilorogmic add occur also in fruit.leaves 3-chloropropylene glycol; Epibloe. C,
<br /> 2109. 740-Chloroethy0theophylline. 7-(2-Chloroerhyl)- and other tissues of dicotyledenous plants: Sondheimer. 110.54. C 32.59%,H 6.38%.Cl 32.08%•O
<br /> 3,7-dihydro•1,3•dimshyl-IH-purine-2,6-diose;Eupnophile. TAsch liharm.293,721 (1960). Finns caffd<add on hydro- CHOHCH,OH. Prepci from glycerol and I
<br /> C,Hi CIN,O,: mol wt 242.68. C 44.55%. H 4.57%, CI lysis Fiedler. Anneimine%Poneh 4.41 (1954). Structure: Quayle. Org. Syn,coll.vol. 1.294(1941).
<br /> 14.61:%, N 23.09%, O 13.1976. Prepn: Cacace el al.. Ann. Fischer, Dangscha4 Ber. 65, 1037 (1932); Barnes et al.. J. Liquid. Sweetish taste. Tendency to tun
<br /> Chim.46,91 (1956); CA,50, 12071 (1956). 'I Am Chem. Sac.72, 4178(1950); Corse et al. Tetrahedron 1 3218. nX 1.4831. bp j„ 213' Week br
<br /> 18, 1207(1962). Synthesis: Panisa el al.. Gazz Chim. Intl 115•)17. 1 in water,a cohol,ether. LC
<br /> 0 CH2CO2<1 86,913(1956). rats: 0.16,0.15 g/kg.C.H.Hine et aL.Arc
<br /> 250(1956).
<br /> xgC� x\ USE: To lower the freezing point of dynar
<br /> an of dye intermediates. As rodent chemoste
<br /> N /_� 2116. Chloromethyl Methyl Ether. Ch
<br /> 0 N a COCCN=Ca on ane; methyl chloromethyl ether; monochl
<br /> cis xaoc a chlorodimethyl ether; CMME. C H,CIO-
<br /> x x 29.84%. H 6.26%, Cl 44.03%, d 19.877,
<br /> v x a Prepd by passing HCI through a mixture
<br /> Long needles from boiling water.mp 121.5-122.5'. Spar- : x0 an methanol: C.S. Marvel,P. K. Porter, Org
<br /> ingly co
<br /> Sol in water. Use of nicotinamide to increase soly: • 377(1941). See alsoBeilstem 1,580(1918)
<br /> Schoen, U.S. pat. 2,755,221 (1956 to Endo Labs.). x at Commercial product usually contaminated
<br /> MERAP CAT: Bronchodilator. methyl ether• q.v. Review and evaluation
<br /> 2110. 2-Chloroethyl Vinyl Ether. (2-Chloroerhoryhth- Hemihydrate• needles from water. Becomes anhydr at anogenicity in laboratory animals: !AR
<br /> ane. C H CIO; mol wt 106.55. C 45.08%. H 6.62%.Cl a i rap 20r. [alb -35.2'(C = 2.8). K at 27 = 2.2 x 239-245(1974).
<br /> 33.28%�O 15.02%. CICH CH OCH=CH. May be prepd ,IU-s, R values: Fiedler, Inc.cit. Soly in water at 25'about Colorless liquid, by 59'. dr 1.0605. ni
<br /> ] z s Note: The technical grade has been lisle
<br /> b the action of solid NaVH + In. upon 00- ,_4%,m more sol in hot water. Alkaline wins acquire an
<br /> dichlorodiethyl ether: Chitwood. Perkins.U.S.pat. 2,104. -c,A'maage Color. Freely ail in alcohol,acetone. Very slightly by the EPA: Second Annual Report on <
<br /> 717(1938 t^Carbide and Carbon Chem.):cf.Creicher et al.. *"wl in ethyl acetate. Heating with dil HCI yields caffein add. 81-43, Dec. 1981) pp 63-67.
<br /> Forms a black cont with iron, said to be res USE: In synthesis of chloromethylated a
<br /> L Am. Chem. Sac.47, 1175(1926). Ini possible for
<br /> Liquid. cill 1.0525. bp7„ 109'. Quite stable to NaOH the blackening of cut and cooked potatoes: Chem. A Ind. 2117. I-Chloro•2-methylpr^gene. a-C
<br /> solns. Even dil acids reduce hydrolysis to acetaldehyde {Lando^)1958,627.
<br /> p y " 90.5ethC 53.l chloride; isocrotyl chlon.
<br /> and ethylene chlorohydrin [2-chlorvethanol]. LD,w orally in `"Y�3'Methyl ethic. Ct,H„O,. 3-jeru(oy/gWnle acid. Cryo- wt 90,55. C 33A3%. H 7.79%,Cl 39.16%.
<br /> .is: 250 mg/kg,Smyth et al.. J. Ind. Hyg. Toxical.31,60 �'UdS from ethyl welsh, + pair ether, rap 196-197. [a] butyraldehyde: Kimmann, Bull Sac. Ch
<br /> (1949).
<br /> -42.8' (ethanol). uv max (ethanol): 325 nm (e 19,200. 163; by isomerization of 3-chloro-2-met
<br /> USE: Mfg anesthetics, sedatives.Cellulose ethers. . 2113. Chlorogenin. (25R)•So-Spirostan•30,6a-diol. 8076 H,SO,: Backhurst et al.. J. Chem.
<br /> 2111. Chloroform. Trichloromethane. CHCI,: mol wt CollOd mol wt 432.62. C 74.9696. H 10.25%, O 14.791/6.
<br /> 119.39. C 10.05%. H 0.84%,Cl 89.1076. Improperly tailed twn from bulbs of the California soap plant,amole: Chia.
<br /> -formyl trichloride". Made from acetone and bleaching Aigalum pomeridianum(DC.)Kunth. Liliaceae: Liang.Nol- cos
<br /> -- let,J.Am.Chem.Sec 57,525(1935). Chloro enin occurs in CxSC-CxCi
<br /> powder by addition of sulfuric add: 2CH3COCH, + j 8
<br /> /are using this section. Consult the trim index before using this section.
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