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9450 1,1,2-Trichloroethane
<br /> 9450. 1,1,2-Trlchloroe rM+iell e. 2 n n; dry cleaning. In the menuf of organic chemicals, pharm, Prepd by direct chlorination of phe
<br /> o ,. H 2.27'8. Cl 79.73%. CH ceuticals, such as chloroacetic acid. 'Tmr. Chios.50, 115(1931):Chulkov et
<br /> (CII. Prepd bycatalytic chlorination of.[bane or el THERAP CAT: Analgesic(inhalation). 1%SSR 3,97(1937); Chem.Zemr.1938,1,
<br /> laaepn.
<br /> U .
<br /> pal. 2,752,401 and Pye. U.S. pat. 2 THERAP CAT(VET): Inhalant anesthetic. (1937).
<br /> built 1956 to Dow): Reynolds. U.S. pat. 2, ,286
<br /> 5 ) Olin Malhiesnn). OR
<br /> met ❑unrotrichloromethane; Freon 11;
<br /> Nnn Ino if liquid: pleasant odor: di° 1.4 6; solidif F^Brn
<br /> 35'; b 13-114•; .0 1.4711. Insol in wa . mise with Arc n CCIIF; mol wt 137.38. C 8.74%, Cl 77.4 1 CI � Cl
<br /> 13.8 %. epm Henne. Organic Reactions 2, 64
<br /> cabal. . . and many other organic liyui LDm orally 9p�
<br /> i 30. 0.58 I/kg.li. F. Smyth yr al.A lnJ. llyg.Astor. Lo 1: Fa Keyes&Claan, Ea Industrial Chemi F. A
<br /> J0,470(19 Low nhcim, K. Moran, Eds. (Wiley-Tote a, Nr.
<br /> Usti. Solvent x fats. waxes. nm I resins, alkaloids York 4th ed., 75)pp 325.330. - CI
<br /> urrira(in o eyes.mucous mManex,end.is big Li id at Scrip below 23.7-. Faint ethe 1 odor. Nun
<br /> rrrinn: I
<br /> mens,Noun:
<br /> Dam able. d�rJ I. :d"5.04(air = U p-1118. bp, s from ligroin. Strong phenolic c
<br /> 23.T; bp. +6.11% b -9.1'o bptm 3.0': bpm -32 V ,but not from alkaline nolo. d 1.
<br /> 9451. 2,2,2.Trichl elhan . Trichlaoo Ili 1 alcoh0 hp. 39.0": bpm - 7% bpm - by -67.8; by Soa
<br /> Y Y(g/100 g of solvent): Accton
<br /> 11 CI O: mol wt 149. 6.08'8.. I1 2.02'%,CI 71.19" -84.- . Crit temp 1911% t Press. .2 atm L'635lb/sq m,� bon tetrachloride 37; diaectune alto
<br /> 110.71"'.. C'CI,C11,011. .pd by reduc[it) of the core abs). ban 1.3865. Dipole ori 0.45. Practically insole. lured alcohol formula 30.400; meth
<br /> uuding.star.acid chlon or acid with lithium alumina wake. Sol in alcohol, eth eI. organic solvents. In, ; Stoddard solvent 16: toluene 100:
<br /> ydride: Snx,g rr ul. A Chem. Sax. 71, 1710(194 toxic an carbon dioxide u[ decomposes into harmla
<br /> maleri Is by flames or hi h i. 0.1.
<br /> nnufaclure by «du on of C ul hydrate wish an ami a salt monohydrate, flaky crystals [p
<br /> USE: In refrigeration achine requiring a refrigerant d
<br /> neonll Chamber/ .S<•haahrcr, par. 2,89tl,J79(1 9 J. Am. Chem. 5'ar.. P 134 (1921)].
<br /> fectiv al negative pr ores. As atom/ propellant. C'av
<br /> Gallery Chem. rianr sy be narc c in high con (rations. hob ether,acetone. pH of sold aq
<br /> Il ygroscopic aid, ethcraJ actor. A[ its ps it cr Fungicide, bactericide. preaervalive.
<br /> Ilio:in rho is riblets, rip at 111%by 151.1 1. Nu e: Consult ant Government egulations on use I.
<br /> of in six, 2 parts water: miscible with alcohol u tit ser . I propelia r 1,11-Tdehloro•2-propanol. 1,1.1
<br /> H of u oln is 5.6, but I prolonged contact with r 54. 3,4 - dehloro-2-nilrophenol. -Nitro-3,4,6.m elwho]; trichloroisopropanol: Ixopra
<br /> ,me fr acid is formal. Keep sad/elated and protected chi ophe ; 2.4,5-trichloro-6•ni(ropheno Dowlep. I. -163.44. C22.04%. H 3.08%, Cl 63.0
<br /> fight orally in rats: 600 mg/kg. Handbook of Toxim Ht SIN .mol wl 242.44. C 29.72%, H 0.8 ,Cl 43.X1' (OH)CH3. Prepd by reaction of chin
<br /> 1. 'ms bromide: Kharasch It al., J. A
<br /> TRY N .7 O 19.8M.. Fitful by dissolving 2, -tnchloo' ,..(1941).
<br /> p 302-303. P in glacial acetic acid and treating with c d our, i< crystals;Tr0'aAP CAT. Hypnotic. aneurhelic. a ohn, Fink. Moncamaish. 58, 73 (1931); Harris a a. Y camphor-like odor. 1
<br /> ' p 161.162'. Sublimes at ordinary
<br /> 9452. Trichloroethylene. Trichloranhenr; ethinyl tri- J r . 1917, 235. 3 parts water: freely sol in alcohol ei
<br /> chloride; 'fri-Clene: Trielene; Toilette: Trichloran; Trichlo. in a cool place. LDm orally in rats:
<br /> ren; Algylen: Trimar. Triline; Tri: Trethylene; Wesirosol; 11 ,J. Pharmacal Esp. Thee 63, 1
<br /> Chlorylen; Gemalgenel Germalgenn. CIHC13; mol wt Cl NOa '3',4',S-Tdehlornealleylanflide. 3.4
<br /> 131.40. C 18.28%. H 0.7776. Cl 80.95%. CCII-CHCI. -Chlorosalicylic acid: 5-chlorosalicy,
<br /> Usually prepd from sym-tetrachloroethane by elimination of CI itis Anobial. C sH1CINO; mol
<br /> HCI (by boiling with lime): Ger.pat. 171,900. By passing `H 2.55%. Cl 33.60'1. N WAR. O 10
<br /> tetrachloroethane vapor over CaClpcatalyst at 300': Ger. ode],U.S. pat. 2,703,332(1955 to
<br /> pal. 263,457; without catalyst at 450-470•: Brit. pat. 575,-
<br /> 530 (1946 to du Pont). Review of mfg processes: S. A. le yellow Crystals from Petr er, mp 92.93'.
<br /> Miller. Chem Prix,. Eng. 47, 268 (1966); Faith, Keyes& SE: To combat the sea Its ey, n eel-like fish ah„, ON
<br /> Clark's 1Q.1rrud Chemical..,. F. A. Lowenheim. M. K. at cks trout. especially in t real es region.
<br /> Moran, Eds. (Wiley-Interwoience. New York.4th ed.. 1975) J Caxx 1
<br /> PP 644-848. Toxicity and metabolism: E. Browning. Tunic- S5. 2,4,3•TE C19Oro In 11. Colluno - Dowiadt Cl
<br /> Uy and Meru6nliam of Industrial Solvents (Eixevier, New C ICAO;mol wt 19 C 36.49%. H 1.53 08-1(r ,' �J\
<br /> York. 1965) PP 189-212. 5 .87%. Prepd by eating 1.2,4.5-tetraebioro one li.' Cl C)
<br /> (hanolic Nan n autoclave at 160-for several
<br /> Nnnhat If chlothle.roform,
<br /> mobile liquid.1 04;Characteristic1,131 ;dor resent- as;
<br /> Ming that of chloroform. d, 1 4904: Jja 1.4695:Jja 1.4649, ^ un yr I.J. em. Sar.1947,233;Agfa,Ger.pa[. �� from chlorobenune rip 246-248". F
<br /> Vapor density: 4.53 (air = 1.00). Solidifies at -84.8' ( Ch Zentr. 1925, 1,2411. salt.
<br /> berm 86.7% bPsm 67.0': hp. 48.0'; helm 71.4': bpm 20.0';
<br /> skin antiseptic and deodorant in se
<br /> bp,a 1.0-; bp, -12.4•: bps -22.8; bpo. -43.8': ii , CAT: Topical antiseptic;antifungal.
<br /> 1.47914: no 1.45560. Practically mmol in water, mise with Cl -y,:.
<br /> ether,alcohol.chloroform. Dissolves most fixed and volatile 71'Iehloroailue. Trichlorommi filar
<br /> oils. Slowly de.(with formn of HCI)by light in the presence �C21HSi; mol wt 135.47. Cl 78.52f.
<br /> of moisture. Trichloroethylene for medicinal purposes may CI ,$HCIs. Pre pd from Si and HCI or h
<br /> contain some thymol or ammonium carbonate (not more CI a of AICI3: Gattermann. Bee 2
<br /> than 20 mg/100 ml)as a stabilizer. Industrial grades of tit- d Der.38, 2226(1905): Stock. Zei
<br /> chloroethylene may contain other stabilizers such as tri. rs:dles from a hol or ligroin. SIron enc r ` ); Schenk in Handbook of Prepare
<br /> ethanolamine stearate and cresol. LDm orally in rats: 4.92 m 67. Sublimes. lip m 248-. bqm 253'. eek m nom.. Tol. 1, O. Brauer. Fd. (Academic
<br /> ml/kg; LC(4 lies)in rats: 8000 ppm.Smyth er al,Am. Ind. aci K at 25' = 4.3 10-1 Soly (g g of s hcn d ed., 1963)pp 691-692.
<br /> Hyg. Astor. J.30,470(1969). 25 acetone 615; ben ne 163: car n tetrachl dc"
<br /> mobile liquid. Fumes in air. Supp
<br /> Caution: Use with adequate ventilation. Preserve Mchlo- et r 325:denatured alcoh formol 0.525:met I Jl 1.3830;dr 1.7417;dis 1.3313. mp -
<br /> roetbylene in sealed, light-resistant ampuls or in frangible, It id petrolatum (at 5(') ' so n if 79: to ne reported as 36.5'. Viscosil in e
<br /> light-resistant glass tubes. Avoid prolonged exposure of the w er <0.2. LDm orally in 0.82 g/kg. De hnua' '200.316 a1 25'. n�n 1.4020Y nkc L3
<br /> product to excessive heal. It must be dispensed in the un- F Fear.2,76(1943). m banana,carbon disulfide.c into
<br /> opened glass container in which it was placed by the menu- mum soh seaquihydrat Dow I B. Flakes[ eP' de. Dipole moment 0.97. LDm o
<br /> factures. co mg
<br /> to US. pat. 1,99 29(19 to Dow)j� ale as H. F. Smyth et al., J. Ind. Hyg. T
<br /> Human Toxicity: Moderate exposures can cause symp- (g 00 g solvent at 2 c acetone 1 denatures
<br /> toms similar to alcohol inebriation. Higher concur can have !banal 24 : ..at ;organic a
<br /> narcotic effect. Deaths occurring after heavy exposure have fo uta 30. 186; eth ne glycol 33; synthesis.
<br /> 11 pH of satd a oln 11.0-13.0. 00 1,. ,2.2•,_
<br /> deco attributedelestablished
<br /> to ventricular fibrillation. Liver injury n not mplex with isobutyl phosphate. His yP� rorth Trlchlorotrle; Iris( -ch 2-
<br /> definitely established in occupational exposures. Found m rhl err. Prefin uillenne-Wallrand et a. Fr.Sint yl)rthonamine; tris(d-chloro
<br /> induce heputocellular carcinomas in National Cancer Insti- (19 to Pec a ). Liquid, 6 94-103'. k"Off Lost; Nitrogen Last; HN3.
<br /> tu[e tests on mice: Chem. d Eng.Newa54,4(Apr. 5. 1976). y q pant .53. C 35.23%. H 5.91%. CI 52.01
<br /> US : Fun tide, bactericide.
<br /> Use: Solvent for lets. waxes. resins, oils, rubber, paints. {1 sCl)a. Prepd by the action of Shinny
<br /> and varnishes. Solvent for cellulose esters and ethers. Used 56, ,4,6-Trichlorophenol. Dowicide 2S; 1 �.;,a ne: Ward, J. Am. Chem, Sox. 57
<br /> for solvem extraction in many industries. In degreasing, in Hs 1,0ml wt 197.46. C 36.49%. O 8.10%• H 2,348 (1937 to Hercules Powder
<br /> Page 1379 Consult rhe r%s5 index 6rforr sing this.sertion. C'un.suIt t
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