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-uu oz3 <br /> i� <br /> cc.3.l--•2 Chrcntc ioxici�. <br /> to sties vete =Giatd razz <br /> aim t...a carc=3.0 :...zzc,::�� of Kaci oils <br /> � aaL"..ats <br /> 65.3.2 umaa a"r4 .=:Le ialagic <br /> 4 Scathes <br /> li <br /> fi6.3.2.1 Sbort-texts Toxicologic furs <br /> E <br /> Zhe chief t i.c reaczian co pet=.1e= hpdracszbans, soca as <br /> l nils. is caa�al neraveis systeta depression (17) . Toxi.cologzcal <br /> e=feats 'are esa_ ectad td resambla those of 'aCetosene. i_e. . a lost oral. <br /> J, eodasaze hi <br /> +' �iias1= dons o� $h aspis�u n hazazd (121 . Prov dad t <br /> adztit i.s as�sr�d tobe4 thn mann oral ?erhal dose of kerosene for as � <br /> boon calerar.ed and less to 6 ounces. Hovavar, twice, this asxsauat h <br /> tb k o�mce has C.asLSad dea<t!i (17) . 1ZLis <br /> 1 p= =may as lav since oral iD3 a values in rays. rabbits =d gui� <br /> { i mak$- Tn fzr-Lt poisonings, dear', slay occur vir..hin 2 :o <br /> 24 haurs after ingeat~on. The di2faxv=s between, cases of tmcamnti- <br /> cated fagestiaa and the lerb-L dosa whaxe asai=atfCa ocezus =.r ce as ' <br /> guea= as a pint and a tesspaoaftti_ The charscrerisric lesion resulting <br /> from asoiratzats is as acure and Often-fzui broacho;=TTmoaia_ tCerasene <br /> and ;e3.ated hydrocarbons are alma irritaziag to the skin and s c==t <br /> cemaranes. Percur-T-eous abso=Prion =y be signifiz== (17) . <br /> Daaaal exao`e to diesel oil has caused mcphrotoxicitp. A. moa <br /> 3.4. <br /> ratio donned his isznds and ares winch diesel oil aver several weeks <br /> experienced syu,,_,ro= of epigastric and laiu pais. ;Ts t ctuzia. <br /> ==ca, =oxv=ia. scror3L svalliug, severe ex+n=sci on and pitting ankle ' <br /> edema_ R$nzl biopsy revem led acvx& rabvlar necrosis v"i.th patchy <br /> lde3eacr2Lzioa and nacrasis of the prnri.21 and discal zmbular epithelium <br /> (3.83.6). mother case was described by 3azxjeur_as ac al. (ISIS) mho E <br /> _eparted acuses oliguric fihluxe im s paciemt who had washed his stair <br /> with diesel oil: A renal biopsy Performed the next dsy showed pular <br /> i dflztian and a pzoli�eratzaa of cells is the glomeruli. Similar <br /> .:%P-ph--orcm:Lc effect~: vnre reposed as a result of i aLatiaa of diesal <br /> ail vapors sic can aver a 10 day period (133.6) . <br /> t <br /> Iiauid aetroleua hydracarboas cause linin or no injury on direct <br /> eye contact_ Kerosene and etroleum oil on r bbic and =man correns � <br /> dna essenrially: .=Ocucl= (I" � <br /> �- ��. 9) . <br /> 65.3.2.2 Chronic Toxicoiogic EEfac= <br /> L Yi E <br /> No stYsdhes were found uhich evaluated the eifeccs o= Long-cera <br /> exaosure ca Duel oils. However. - n=ercus evidemzology series <br /> (" evaluac1:g the p e££eets o= Pat= leum e=osure nave bees conduc=ed_ <br /> i Uhilc rest have shown overall sr�_,d=dz:ed =orrmUcy racias re be lover , <br /> I than chose of the general PoPulaon. elevated m=bers of deaths have } <br /> ` been Observed for cancers at: several. sites. However. chase ele-var onz <br /> Fw ate rot -=etmc caruzstzrtcly is all of the smyrus. Caaca_s h_v <br /> E. e been <br /> / t <br /> rr a <br /> IIF .. <br /> [{2 <br />