|
MATERIAL SAFETY DATA SHEET UPDATES AVAILABLE AT WWW.GREENBOOK.NET 1
<br /> LORSBAN* -4E excessive exposure to chlorpyrifos may be headache, FIRE & EXPLOSION HAZARDS: Foam fire extin-
<br /> dizziness, incoordination, muscle twitching, tremors, guishing system is preferred because uncontrolled wa-
<br /> INSECTICIDE (NAF nausea, abdominal cramps, diarrhea, sweating, pin- I ter can spread possible contamination. Toxic,irritating
<br /> 1��` point pupils, blurred vision, salivation, tearing, tight- gases may be formed under fire conditions. Rapid de-
<br /> II ness in chest,excessive urination,convulsions. Chlor- composition above 320-392'F(160-200'C)can occur.
<br /> Emergency Phone: 800-992-5994 pyrifos produced mild adrenal effects when fed to rats, Violent rupture due to over-pressurization may occur
<br /> r' Dow AgroSciences LLC but only at doses that greatly exceeded any exposures at temperatures generated during a fire.
<br /> Indianapolis,IN 46268 that would be received during normal use of this prod- j FIRE-FIGHTING EQUIPMENT:Use positive-pressure
<br /> Effective Date: 2/28/00 uct. Solvent has been reported to cause liver,kidney, self-contained breathing apparatus and full protective
<br /> Product Code: 47602 and blood effects at high exposure levels. Xylene is clothing.
<br /> MSDS:005688 reported to have caused hearing loss in laboratory an-
<br /> imals upon exposure to high concentrations;such ef-
<br /> 1. PRODUCT AND COMPANY IDENTIFICATION: fects have not been reported in humans. For cumene, ACTION TO TAKE FOR SPILLSILEAKS: Absorb
<br /> PRODUCT:Lorsban'-4E Insecticide(NAF 163) in animals,effects have been reported on the following spills with inert absorbent material such as dry sand.
<br /> COMPANY IDENTIFICATION: organ: eye(cataract). Thoroughly wash body areas which come into contact
<br /> Dow AgroSciences CANCER INFORMATION:Chlorpyrifos did not cause with this product. Contain spill to keep out of sewers.
<br /> 9330 Zionsville Road cancer in laboratory animals. Xylene was not found Report large spills to Dow AgroSciences at 800-992-
<br /> Indianapolis, IN 46268-1189 to be carcinogenic in a National Toxicology Program 5994.
<br /> - bioassay in rats and mice. 7, HANDLING AND STORAGE:
<br /> 2. COMPOSITION/INFORMATION ON INGREDI- TERATOLOGY(BIRTH DEFECTS): Chlorpyrifos did
<br /> ENTS: not cause birth defects in laboratory animals. Solvent PRECAUTIONS TO BE TAKEN IN HANDLING AND
<br /> chlorpyrifos: GAS u 002921-88-2 44.9% was toxic to the fetus in laboratory animal tests,but STORAGE:Keep out of reach of children. Do not get
<br /> 0.0-diethy- only at doses that were toxic to the mothers. Very high in eyes, on skin or clothing. Avoid breathing vapor
<br /> 0-(3.5,13-trichloro-2- and spray mist. Users should wash hands before eat-
<br /> inert concentrations of solvent(producing severe toxicity to
<br /> Inert Ingredients,total,induding: 55.1% ! adult animals) induced an increase in cleft palate in ing, drinking, using tobacco, or using the toilet. For
<br /> xylene Range Aromatic mice,which is a common developmental abnormality handling relative to the end-use of this product,read
<br /> Solvent GAS a 064742-95-6 the product label. Store in original container in a dry
<br /> in mice and is associated with stress to the maternal
<br /> Trimethylbenzene GAS a 000095-63-6 !
<br /> animals. No malformations were induced at exposures storage area. Do not sore above 100'F for extended
<br /> i Cumene GAS u 000098-82-8 less than those causing severe toxicity to the adult i. periods of time. Storage below 20'F may result in the
<br /> xylene CAS fl 001330-20-7 formation of crystals. If product crystallizes,store at
<br /> Ethytoiuene GAS n 025550-14-5 animals. This product contains low levels of xylene. 50-70'F and agitate to re-dissolve crystals.
<br /> This document is prepared pursuant to the OSHA Haz- Exaggerated doses of xylene given orally to pregnant
<br /> and Communication Standard(29 CFR 1910.1200). In mice resulted in an increase cleft palate,a common 8. EXPOSURE CONTROLS/PERSONAL PROTEC-
<br /> addition, other substances not 'Hazardous' per this developmental abnormality in mice. Inhalation expo- TION:
<br /> OSHA Standard may be listed. Where proprietary in- sure of pregnant animals xylene resulted in toxicity
<br /> to the fetus but did not cause any birth defects. These precautions are suggested for conditions where
<br /> gredient shows,the identity may be made available as a potential for exposure exists. Emergency conditions
<br /> provided in this standard. REPRODUCTIVE EFFECTS:Chlorpyrifos did not in- may require additional precautions.
<br /> terfere with fertility in reproduction studies in laboratory EXPOSURE GUIDELINE(S):
<br /> 3. HAZARDOUS IDENTIFICATIONS: animals. Some evidence of toxicity to the offspring oc-
<br /> curred,but only at a dose high enough to produce sig- Chlorp3yrifos: ACGIH TLV and OSHA PEL are 0.2
<br /> EMERGENCY'OVERVIEW mg/M ,Skin. ACGIH classification is A4.
<br /> Hazardous chemical. Red liquid with solvent-type reproduction
<br /> ction[std the parent animals. Ina 3-generation Aromatic 100 (xylene range aromatic solvent): none
<br /> odor. reproduction study on the solvent,the only effects ob- established.
<br /> May cause eye irritation or corneal injury. Prolonged served were at exposures that produced severe toxicity Trimethylbenzene: ACGIH TLV and OSHA PEL are
<br /> exposure may cause skin irritation. LD50 for skin ab- to the parent animals. 25 ppm.
<br /> sorption in rabbits is>5000 mg/kg.Oral LD50 for rats is 4. FIRST AID: Cumene(isopropyl benzene): ACGIH TLV and OSHA
<br /> 776 mg/kg(males)and 300 mg/kg(females). LC50 for PEL are 50 ppm.
<br /> EYES:Irrigate with flowing water immediately and con-
<br /> rats is 2.7 mg/L for 4 hours. Cholinesterase inhibitor. Xylene: ACGIH TLV and OSHA PEL are 100 ppm
<br /> Toxic to aquatic organisms,birds,and fish. tinuously for 15 minutes. Consult medical personnel. TWA, 150 ppm STEL.ACGIH classification is A4.
<br /> EMERGENCY PHONE NUMBER:800-992-5994 SKIN: Immediately wash with plenty of soap and war. Ethyltoiuene: Dow AgroSciences Industrial Hygiene
<br /> POTENTIAL HEALTH EFFECTS: This section in- ter. Remove contaminated clothing and shoes. Wash Guideline is 10 ppm.
<br /> cludes possible adverse effects which could occur if clothing before reuse. Destroy and dispose of contam- PELs are in accord with those recommended by OSHA,
<br /> this material is not handled in the recommended man- inated shoes and other leather articles such as belts as in the 1989 revision of PELs.
<br /> and watchbands.
<br /> ner. A'skin'notation following the exposure guideline refers
<br /> l cen-
<br /> t
<br /> i
<br /> i
<br /> i
<br /> h
<br /> Call Caa physician or poison control EYE:May cause moderate eye irritation and/or corneal INGESTION: to the potential for dermal absorption of the material.
<br /> ter immediately. Do not induce vomiting. contains an
<br /> injury. Vapors may irritate the eyes. aromatic petroleum solvent. Do not give anything by It t intended to alert the reader that inhalation may
<br /> � SKIN:Prolonged exposure may cause moderate skin not be the only route of exposure and that measures
<br /> irritation. A test in guinea pigs indicated that this prod- mouth to an unconscious person. to minimize dermal exposures should be considered.
<br /> uct may have weak skin sensitization potential. How- INHALATION:Remove to fresh air and if not breathing ENGINEERING CONTROLS:Provide general and/or
<br /> ever, experience in the manufacture and use of this give artificial respiration,preferably mouth to mouth. local exhaust ventilation to control airbome levels be-
<br /> product has not provided evidence for skin sensitiz- NOTE TO PHYSICIAN: Because rapid absorption low the exposure guidelines. Use only with adequate
<br /> ing properties. The product did not sensitize human may occur through the lungs aspirated and cause ventilation.
<br /> subjects when tested at an end-use dilution- A single systemic effects, the decision of whether to induce RECOMMENDATIONS FOR MANUFACTURING,
<br /> prolonged exposure is not likely to result in the material vomiting or not should be made by a physician. If COMMERCIAL BLENDING, AND PACKAGING
<br /> d
<br /> f
<br /> is performed, suggest endotracheal and/or
<br /> being absorbed through the skin in harmful amounts. lavage WORKERS:
<br /> The LD50 for skin absorption in male rats is >5000 esophageal control. Danger from lung aspiration must RESPIRATORY PROTECTION: Atmospheric levels
<br /> mg/kg. be weighed against toxicity when considering empty- should be maintained below the exposure guidelines.
<br /> „r INGESTION: Single dose oral toxicity is moderate. ing the stomach. If exposed, plasma and red blood When respiratory protection is required,use a NIOSH
<br /> The oral LD50 for rats is 776 mg/kg(males)and 300 cell cholinesterase tests may indicate significance of approved air-purifying or positive-pressure supplied-air
<br /> exposure (baseline data are useful). Atropine, only
<br /> to nor/kg(females). Small amounts swallowed incidental by injection,is the preferable antidote. Oximes,such respirator depending c the potentialodidairborne where
<br /> normal handling operations are not likely to cause as 2-PAM/ roto am,may be therapeutic if used earl the ex For emergency and other conditions where
<br /> injury;however,swallowing larger amounts may cause p p y p y� the exposure guideline may be greatly exceeded,use
<br /> injury,even death. If aspirated(liquid enters the lung), however,use only in conjunction with atropine. In case a NIOSH
<br /> p' (q g), approved positive-pressure, self-contained
<br /> may cause lung damage or death due to chemical of severe acute poisoning, use antidote immediately breathing apparatus or positive-pressure airline with
<br /> pneumoafter establishing an open airway and respiration. Ex-
<br /> ria. posure may increase"myocardial irritability". Do not auxiliarysearcontainedairsupply.Iaconfinedorpoorly
<br /> INHALNHALATION: The aerosol LCso for rats is 2.7 ventilated areas, use a NIOSH approved positive-
<br /> mg/L for 4 hours. Excessive exposure may pro- administer sympathomimetic drugs unless absolutely pressure supplied-air respirator.
<br /> duce organophosphate-type cholinesterase inhibition- necessary.Supportive care.Treatment based on judg- SKIN PROTECTION:Use protective clothing impervi-
<br /> Excessive vapor concentrations are attainable and ment of the physician in response to reactions of the ous to this material. Selection of specific items such
<br /> could be hazardous on single exposure. Excessive patient. as faceshield,gloves,boots,apron or full body suit will
<br /> exposure to solvent may cause respiratory irritation S. FIRE FIGHTING MEASURES: depend on operation. Remove contaminated clothing
<br /> and central nervous system depression. Signs and immediately,wash skin area with soap and water,and
<br /> symptoms of central nervous system depression,are FLASH POINT:106'F(41'C) launder clothing before reuse. Items which cannot be
<br /> in order of increasing exposure,headache,dizziness, METHOD USED:TCC decontaminated,such as shoes,belts and watchbands
<br /> drowsiness,and incoordination. FLAMMABLE LIMITS should be removed,destroyed and disposed of.
<br /> SYSTEMIC (OTHER TARGET ORGAN EFFECTS): LFL: 1% EYE PROTECTION:Use chemical goggles. If vapor
<br /> Excessive exposure may produce organophosphate- UFL:6%(xylene range aromatic solvent) exposure causes eye discomfort, use a NIOSH ap-
<br /> type cholinesterase inhibition. Signs and symptoms of EXTINGUISHING MEDIA:Foam,CO2,dry chemical proved full-face respirator.
<br /> Database and format copyright @ by C&P Press. All rights reserved. Powered by C&P Press.
<br />
|