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ARI�EMA SAFETY DATA SHEET <br /> RILSANO 5956 GREY RDP 15-10 ES <br /> Oral: <br /> No deaths occurred. (Rat) LDO>2,000 mg/kg. <br /> Dermal: <br /> No deaths occurred. (Rat) LDO >2,000 mg/kg. <br /> Skin Irritation: <br /> Not irritating. (In vitro) <br /> Eye Irritation: <br /> Not corrosive(Bovine cornea) <br /> Skin Sensitization: <br /> Not a sensitizer. LLNA: Local Lymph Node Assay. (Mouse) No effect is reported. <br /> Repeated dose toxicity <br /> Subchronic dietary administration to rat, dog/No adverse systemic effects reported. <br /> Genotoxicity <br /> Assessment in Vitro: <br /> No genetic changes were observed in laboratory tests using: bacteria <br /> Other information <br /> The information presented is from representative materials with this Chemical Abstract Service(CAS) Registry <br /> number. The results vary depending on the size and composition of the test substance. <br /> Data for Carbonic acid calcium salt(1:1)(471-34-1) <br /> Acute toxicity <br /> Oral: <br /> Practically nontoxic. (rat) LD50=6,450 mg/kg. <br /> Dermal: <br /> No deaths occurred. (rat) LDO >=2,000 mg/kg. <br /> Inhalation: <br /> No deaths occurred. (rat)4 h LCO>=3 mg/I. signs: No specific toxic effects(aerosol, Maximum <br /> concentration technically possible) <br /> Skin Irritation: <br /> Not irritating. (rabbit) Irritation Index: 0.0/8.0. (4 h) <br /> Eye Irritation: <br /> Causes mild eye irritation. (rabbit) <br /> Skin Sensitization: <br /> Not a sensitizer. LLNA: Local Lymph Node Assay. (mouse) No effect is reported. <br /> Repeated dose toxicity <br /> Repeated oral administration to rat, mouse/No adverse systemic effects reported. <br /> Genotoxicity <br /> Product code: A09469 Version 1.0 Issued on: 05/15/2015 Page: 9/ 16 <br /> Quick-FDS[17303-32698-27051-0167981-2015-05-16-09:04:58 <br />