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9900. Vinylidene Chloride. /,/-Dichlomethene: 04' cin Pi •
<br />di loraethy/ene; asyrn-dichloroethylene. C2H2 C12; mol wt
<br />45.65. C 24.78%, H 2.08%, Cl 73.14%. CF-15 --CC15. Prepn from ethylene chloride: Reilly. U.S. pat. 2,14.0,548 (1938 to Dow). By dehydrochlorination of 1,1.2-trichloroethane:
<br />coorad, Gould. U.S. pat. 2,989,570 (1961 to Ethyl Corp.).
<br />Liquid. Mild, sweet odor resembling that of chloroform.
<br />41 1.2129. mp —122.5. bp,6,5 31.7. ni° 1.4249. Flash pt
<br />-15. Practically insol in water. Sol in organic solvents. Al romps above 0° and especially in the presence of oxygen
<br />or other suitable catalysts polymerizes to a plastic. Several
<br />ahibitors to preserve the monomer have been invented.
<br />Cocontrolled polymerization may lead to explosive reaction
<br />products with oxygen or ozone: Reinhardt, Chem. Eng. 25, 2136 (1947).
<br />LsE: Intermediate in the production of "vinylidene poly-
<br />plastics" such as Saran and Velon. Caution: Irritant to
<br />, mucous membranes; narcotic in high concentrations.
<br />ins caused liver, kidney injury in exptl animals: Irish in ,
<br />kaustrial Hygiene and Toxicology vol. 2, F. A. Patty, Ed.
<br />tlaterscience, New York, 2nd ed., 1962) pp 1305-1307; Preadergast et al.. Toxicol. AppL PharmacoL 10, 270 (1967).
<br />r6.6. Ethylidene Chloride.
<br />Ali liquid; odor and taste as of chloroform. dr 1.1757:
<br />elution: Narcotic in high concns.
<br />aol wt 98.97. C 24.27%, H 4.07%, Cl 71.65%. CI-13 -
<br />1.1(180. bp 57.3*: Mumford. Phillips, J. Chem. Soc.
<br />. miscible with alcohol.
<br />75. mp --98'. nil 1.4167. Sol in about 200 parts
<br />Prepd by the action of PCI5 on acetaldehyde.
<br />1,1-Dichloroethane.
<br />i.,1 "field-aro te:
<br />9552. Trichloroethylene. Trichloroethene: ethinYi
<br />chloride; Tri-Cleric; Trielene; Trilene; Trichloran;
<br />ren; Algylen; Trimar; Triline; Tri; Trethylene; Wearenlit
<br />Chlorylen; Gernalgene; Gerrnalgene. C5HC1 itid 114
<br />131.40. C 18.28%, H 0.77%, CI 80.95%. ca;-aia.-;
<br />Usually prepd from sym-tetrachloroethane by elimmatioaft.:
<br />HC1 (by boiling with lime): Ger. pat. 171,900. By
<br />tetrachloroethane vapor over CaC12 catalyst at 300%.-Irsat.2.:„
<br />pat. 263,457; without catalyst at 450-470': Brit. pat.
<br />530 (1946 to du Pont). Review of mfg processes;
<br />Miller. Chem. Chem. Process Eng. 47, 268 (1966); Faith, KCVO 11,1"; Clark's Industrial Chemicals, F. A. Lowenheim. a K. 1
<br />Moran. Eds. (Wiley -Interscience. New York, 4th ed... If*
<br />pp 844-848. Toxicity and metabolism: E. Browning. Twit.
<br />icy and Metabolism of Industrial Solvents (Elsevier.. Piear„
<br />York. 1965) pp 189-212. Toxicity data: Smyth et al.."*".
<br />Ind. Hyg. Assoc. J. 30, 470 (1969). 1- ....tilt,
<br />Nonflammable, mobile liquid. Characteristic odormemo
<br />bling that of chloroform. d: 1.4904; clis 1.4695; dr 1.461(
<br />Vapor density: 4.53 (air =. 1.00). mp —84.8'. bp,. W.:*
<br />bp 67.0'; bp,00 48.0'; bp100 31.4'; bp, 20.0'; bPla -7,:f.:1- bp„ —12.4; bp, —22.8'; bp,.0 —43.8% ng 1.47914;
<br />45560. Practically insol in water; misc with ether. aloolm"_
<br />chloroform. Dissolves most fixed and volatile 0i13. NOW
<br />dec (with formn of HC1) by light in the presence of meant*
<br />Trichloroethylene for medicinal purposes may contain tilt
<br />thymol or ammonium carbonate (not more than 20 mew'
<br />ml) as a stabilizer. Industrial grades of trichloroallYegge
<br />may contain other stabilizers such as triethanolamine
<br />rate and cresol. LD„ orally in rats: 4.92 ml/kg; LC(4 kini
<br />, in rats: 8000 ppm (Smyth).
<br />Caution: Use with adequate ventilation. Preserve trict.
<br />roethylene in sealed, light 'resistant ampuls or in frag,,T.
<br />light -resistant glass tubes. Avoid prolonged exposure Ix::
<br />product to excessive heat. It must be dispensed in the7-
<br />40,24 glass container in which it was placed by the manu-
<br />starer. Osman Toxicity: Moderate exposures can cause symp-
<br />gas similar to alcohol inebriation. Higher concns can have
<br />sigotie effect. Deaths occurring after heavy exposure have
<br />to attributed to ventricular fibrillation. Liver injury is not
<br />orwitely established in occupational exposures. Found to
<br />Ore hepatocellular carcinomas in National Cancer Insti-
<br />"attests on mice: Chem. & Eng. News 54, 4 (Apr. 5, 1976).
<br />pig Solvent for fats, waxes, resins, oils, rubber, paints,
<br />ad varnishes. Solvent for cellulose esters and ethers. Used
<br />w sgvent extraction in many industries. In degreasing, in
<br />cleaning. In the manuf of organic chemicals, pharma-
<br />aikals, such as chloroacetic acid.
<br />low CAT: Inhalation analgesic.
<br />our CAT WED: Inhalation anesthetic.
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