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3327
<br />T1M000 HR: 1
<br />1,2-TRICHLOR0-2,2-DIFLUOROETHANE
<br />CAS: 354-21-2 NIOSH: KI 1435000
<br />mf: CHC13F2 mw: 157.37
<br />SYNS:
<br />1.1-DIFLUORO-1 ,2.2-TRICHLORO- UCON FLUOROCARBON 122
<br />ETHANE
<br />TOXICITY DATA: CODEN:
<br />on -rat LDLo:7500 mg/kg HXPHAU 20(Pt 1),-
<br />459,66
<br />ihl-rat LCLo:4000 ppm/4H UCMH** 15NOV62
<br />THR: Mildly toxic by ingestion and inhalation. When
<br />heated to decomposition it emits very toxic fumes of R-
<br />and Cr. See also CHLORINATED HYDROCARBONS,
<br />ALIPHATIC and FLUORIDES.
<br />TIM500 HR: 1
<br />TRICHLORO ESTERTIN
<br />NIOSH: WH 8240000
<br />SYN: ESTERTRICHLOROSTANNANE
<br />TOXICITY DATA: CODEN:
<br />unr-rat LD50:5500 mg/kg TIUSAD 107,1,76
<br />OSHA PEL: TWA 0.1 mg(Sn)/m3
<br />ACGIH TLV: TWA 0.1 mg(Sn)/m3 (skin)
<br />NIOSH REL: (Organotin Compounds) TWA 0.1 mg(Sn)/m3
<br />THR: When heated to decomposition it emits toxic fumes
<br />of Cr . See also TIN COMPOUNDS and ESTERS.
<br />TIM750
<br />HR: 3
<br />1,1,1-TRICHLOROETHANE
<br />CAS: 71-55-6
<br />NIOSH: KJ 2975000
<br />DOT: 2831
<br />ME C2H3C13
<br /> mw: 133.40
<br />PROP: Colorless liquid. Bp: 74.1°, fp: —32.5°, flash p:
<br />none, d: 1.3376 @ 20°/4°, vap press: 100 mm @ 20.0°.
<br />Insol in water; sol in acetone, benzene, carbon tetrachloride,
<br />methanol, ether.
<br />SYNS:
<br />AEROTHENE TT
<br />CHLOROETENE
<br />CHLOROETHENE
<br />CHLOROTHANE NU
<br />CHLOROTHENE
<br />CHLOROTHENE (INHIBITED)
<br />CHLOROTHENE NU
<br />CHLOROTHENE VG
<br />CHLORTEN
<br />INHIBISOL
<br />METHYLCHLOROFORM
<br />METHYL CHLOROFORM (ACGIH,
<br />DOT)
<br />METHYLTRICHLOROMETHANE
<br />NCI-004626
<br />RCRA WASTE NUMBER U226
<br />SOLVENT 111
<br />STROBANE
<br />a-T
<br />1.1.1-TCE
<br />1.1.I-TRICHLOORETHAAN
<br />(DUTCH)
<br />1. I .1-TRICHLORAETHAN (GER-
<br />MAN)
<br />TR ICHLOR0-1.1,1-ETHANE
<br />(FRENCH)
<br />a-TRICHLOROETHANE
<br />I , I .1-TRICLOROETANO (ITALIAN)
<br />TRI-ETHANE
<br />1,1,1-TRICHLOROETHANE TIM750
<br />TOXICITY DATA: CODEN:
<br />eye-man 450 ppm/8H BJ1MAG 28,286,71
<br />skn-rbt 5 g/12D-1 MLD
<br />AIHAAP 19.353,58
<br />skn-rbt 500 mg/24H MOD
<br />28ZPAK -,28,72
<br />eye-rbt 100 mg MLD
<br />AIHAAP 19.353,58
<br />eye-rbt 2 mg/24H SEV
<br />28ZPAK -,28,72
<br />dnr-esc 500 mg/L
<br />PMRSDJ 1,195,81
<br />otr-mus:emb 20 mg/L
<br />CALEDQ 28,85,85
<br />on-rat TDLo:43 mg/kg (1-22D
<br />TJADAB 29(2),25A,84
<br />preg/21D post):TER
<br />ihl-rat TCLo:2100 ppm/24H
<br />TOXID9 1,28,81
<br />(14D pre/1-20D preg):TER
<br />ihl-man LCLo:27 g/rn i/lOM
<br />JOCMA7 8,358,66
<br />ihl-man TCLo:350 ppm:CNS
<br />WEHSAL 10,82,73
<br />orl-hmn TDLo:670 mg/kg:GIT
<br />NTIS** PB257-185
<br />ihl-hmn TCLo:920 ppm/70M: AIHAAP 19,353,58
<br />EYE ,CNS
<br />ihl-man TCLo:200 ppm/4H:CNS
<br />ATSUDG 5.96,82
<br />orl-rat LD50:10300 mg/kg NTIS** PB257-185
<br />ihl-rat LC50:18000 ppm/4H
<br />28ZPAK -,28.72
<br />ipr-rat LD50:5100 mg/kg NTIS** PB257-185
<br />orl-mus LD50:11240 mg/kg NTIS** PB257-185
<br />ihl-mus LC50:3911 ppm/2H
<br />SAIGBL 13,226,71
<br />ipr-mus LD50:4700 mg/kg TXAPA9 13.287,68
<br />on-dog LD50:750 mg/kg FMCHA2 -,C242,83
<br />ipr-dog LD50:3100 mg/kg TXAPA9 10,119,67
<br />ivn-dog LDLo:95 mg/kg HBTXAC 5,72,59
<br />ihl-cat LCLo:600 mg/m3/4H
<br />85GMAT -.38,82
<br />orl-rbt LD50:5660 mg/kg AIHAAP 19,353,58
<br />skn-rbt LDLo:1 g/kg 85GMAT -.38.82
<br />scu-rbt LDLo:500 mg/kg HBTXAC 5,72,59
<br />orl-gpg LD50:9470 mg/kg AIHAAP 19,353,58
<br />IARC Cancer Review: Animal Inadequate Evidence
<br />IMEMDT 20,515,79. NCI Carcinogenesis Bioassay (ga-
<br />vage); Inadequate Studies: mouse, rat NCITR* NCI-CG-
<br />TR-3,77. Community Right To Know List. Reported in
<br />EPA TSCA Inventory. EPA Genetic Toxicology Program.
<br />OSHA PEL: TWA 350 ppm
<br />ACGIH TLV: TWA 350 ppm; STEL 450 ppm
<br />DFG MAK: 200 ppm (2080 mg/m3); BAT: blood 55 lig/d1
<br />NIOSH REL: (1,1,1-Trichloroethane) CL 350 ppin/15M
<br />DOT Classification: ORM-A; Label: None; Poison B; La-
<br />bel: St Andrews Cross
<br />THR: Poison by intravenous route. Moderately toxic by
<br />ingestion, inhalation, skin contact, subcutaneous and intra-
<br />peritoneal routes. An experimental teratogen. Human sys-
<br />temic effects by ingestion and inhalation: conjunctiva irrita-
<br />tion, hallucinations or distorted perceptions, motor activity
<br />changes, irritability, aggression, hypermotility, diarrhea,
<br />nausea or vomiting and other gastrointestinal changes. Ex-
<br />perimental reproductive effects. Mutagenic data. A human
<br />skin irritant. An experimental skin and severe eye irritant.
<br />Narcotic in high concentrations. Causes a proarrhythmic
<br />activity which sensitizes the heart to epinephrine-induced
<br />arrhythmias. This sometimes will cause cardiac arrest, par-
<br />ticularly when this material is massively inhaled as in drug
<br />abuse for euphoria.
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