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wsL OILS <br /> 66-29 <br /> Anchr3CenP <br /> Anthracene assert: phototoxic and photoallergic action on the <br /> human skin. It is carcinogenically inactive (12). Va <br /> mutagenicity studies have produced negative responses (2315 ;sous <br /> lowest toxic. oral dose in the rac is 10 9/kg (47). ) The <br /> 66.3,4 rcxicolovy of Fuel oil Additives <br /> M The coxicicy of selected fuel oil additives is outlined below. <br /> c-Jr-OM2 n—ds <br /> Manganese affects the C:75. on _ <br /> chronic stly in th <br /> form known as mangznisra which iistisi.milar Oto mFarkinsenis@e <br /> Jsually mnnganism occurs after 1-2 years exposure to manganese oxides <br /> although it may develop after only a few months, Initial syntpeems <br /> include hcacache, asthenia <br /> sleep and personality (loss of strength• and energvi, restless <br /> changeis. <br /> phsse with visual hallucinations. double <br /> followed visa vision, impxiredy an Cehaa=fnge I <br /> Suncontrollable impuEses, mental confusion and euphoria. In advanced I <br /> Stages. the patient experiences -xcessive salivation, muscle weakness, <br /> muscle rigidityex <br /> an:, tremor of the upper tremities and head, and impaired <br /> gait. In mang ..m with neurologic svmpcoms, the course is frequently <br /> progressive z-Lchough some cases are stationary and others recover <br /> (2,46), <br /> ` • InhaLacion of high concentrations of manganese oxide causes metal <br /> � fume fever a 24.48 � <br /> s hour illness characterized by chills, fever, <br /> aching muscEes, dry mouth and throat, and headache (46). <br /> Magnesium oxide Eames are irricacing to the eves and nose. It <br /> also causes metal fume fever which is a 24-48 hour influenza-type <br /> illness (46). <br /> • e <br /> Alum' um O.c'de <br /> Aluminum oxide is a nuisance dust•;+hich has little adverse effect <br /> on she lunge ac lou exposure levels. Excessive concentrations may <br /> a cause deposits in the eyes, ears and nasal Passages or may cause mild <br /> injury co the skin and <br /> s mucous membranes (46). <br /> � <br /> ser,ides <br /> In general, peroxides are strong Oxidizing agents capable of skin <br /> irritation, burns or eve damage (200). <br /> i <br /> f <br /> i <br /> 6/87 <br />