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I <br /> kUT0H0Tr7E GASGL=F- k � <br /> 65-31 <br /> na T aMA <br /> Tetrame - <br /> thyi lead affects the nervous system in ani=!z and cages <br /> signs of increased irritability. Although not docu=znted, it is <br /> expected to produce psychosis, mania and convulsions i:. <br /> : nva the rat, an oral las, of 109 mg/kg was reported (47) . � (4b) . <br /> i <br /> Lt is 1'"ly that intoxication by tetramethyl lead will be similar <br /> El to that caused by tatraerhvl lead4 ) <br /> taxi be found in Chaptar 54 of the Iastall�no Restoration program <br /> 4 Toxicology Guida, Volume 2. <br /> u (MKr) <br /> Ln its conceuc=cad forte. MM is highly toxic by all routes of 3 <br /> exposure. The primary site of action in anixoals is the CHS, where eha <br /> effects of 14!! are similar to chose causad by tatraat:hyl lead. TEha <br /> oral Laso in the rat is 50 mg/kg, Human exposure data are limited. It <br /> Ls expectad that; when MKT is blended with fuels, it has a low order of <br /> toxicity. <br /> k i <br /> Concentrated KKT penetrates the skin readily. When 5-15 mL was <br /> spilled an a worker's skin, nausea, headache and giddiness resulted in <br /> a 2-5 mita period; however. gasoline solutions are not as readily <br /> absorbed as the pure material (2.1937,1409) . <br /> Ethyl eng—dibromi d P_ (IDB) <br /> ®B is L=1. aging to the eyes and ==ons mambrsms. <br /> It also <br /> causes Symptoms of CBIS depression. Acute asPostsres hsva resulted- in <br /> long, liver and kidney damage (1745,1759.38,54). UM is care3aoWj=ie <br /> } in rodants by oral. inhalation and dermal roucas (142.1606,1743,1744), <br /> 1 4 ACCM has classified EDB as a suspected buzan careinogan with a <br /> recommendation chart exposure be avoidad (3) . The oral Laso in tha rat <br /> { is 146 mg/kg (1759) . Mara information on IDB can bs found 1.a Cbaptar <br /> a5 of the Installation Restoration Program Toxicology Cuide, Volt2. <br /> 1_ <br /> Acute ingestion or inhalation of 1,2-aichloroethane results in <br /> .a • symptoms of CNS depression, gastrointestinal upset and systemic injury <br /> to the liver. kidneys and lungs (12) . The oral Las. in the rat is 678 <br /> Mg/kg (47). !'lore information on L,2-di,ehloroachmaim can be found in <br /> Chapter 9 of the <br /> VolumInstallatiDn Restoration Program Toxicology Cuide, <br /> 1, v <br /> (MTBE) <br /> i <br /> :In rats. an oral LD-so of 4 mL/kg was reported (1937). In <br /> i recently conducted acute and subchronic casts, it was reported that <br /> HTBE caused a deepening of barbiturate sleep. a reduction of <br /> a 6/87 <br /> �a <br /> Ei I <br /> i <br /> i. <br />